An internally developed knowledge transfer methodology ensures at Credit Suisse that irreplaceable know-how (implicit and explicit) remains within the firm – even when keypersons leave, e.g. retirement, internal job mobility, extended absence or general leaving. The methodology tested in theory and in praxis was developed by supporting over 70 keypersons and became part of the organisation in 2008. By covering general aspects of knowledge transfer as well as enhancing the human capital development in the business, the methodology provides a basis for organisational development: Due to transparent tasks and functions efficient and sustainable changes are possible.